The late-stage trial of Revlimid (lenalidomide) for the treatment of advanced prostate cancer has been discontinued after preliminary data shows that it does not extend survival! The independent monitoring committee recommended that the pivotal Phase III Mainsail trial be halted after it determined that adding Revlimid to standard treatments would not significantly increase the overall [...]
Health News First Drug Ok'd to Combat Spreading Basal Cell Skin Cancer Print E-mail MONDAY , Jan . 30 HealthDay News The U.S . Food and Drug Administration on Monday approved a drug to treat the most common form of skin cancer , basal cell . carcinoma Erivedge vismodegib is the first drug sanctioned in the United States to treat basal cell skin cancer that has metastasized , or spread . The once-daily pill is also designed for cases deemed unsuitable for surgery or radiation , the agency said in a news . release This usually slow-growing , painless form of cancer starts in the epidermis , the top layer of skin . Frequent exposure to sunlight and other forms of ultraviolet radiation are the typical causes , the FDA . said Researchers evaluated the safety and effectiveness of Erivedge in a
Health News Erivedge Approved to Treat Basal Cell Carinoma Print E-mail MONDAY , January 30 HealthDay News Erivedge vismodegib has been approved by the U.S . Food and Drug Administration to treat the most common form of skin cancer , basal cell carcinoma , the agency said . Monday The drug was approved for people for whom surgery or radiation aren't options , and for people with basal cell that has spread to other parts of the body , according to an FDA news . release Basal cell usually is a slow-growing , painless type of cancer that begins in the top layer of skin , often on areas most exposed to the . sun Erivedge was evaluated in clinical studies involving 96 people with basal cell carcinoma . The most common side effects included muscle spasms , hair loss , weight loss , nausea ,
Treatment of high-grade prostate cancer with brachytherapy significantly reduced prostate cancer-specific mortality compared with external beam radiation alone, results of a large study showed.
Health News Test Might Predict Risk of Lung Cancer's Return Print E-mail THURSDAY , Jan . 26 HealthDay News A new industry-funded study suggests that a molecular test can provide insight into whether patients are at high risk of a relapse after surgical treatment for a form of lung cancer . The test , which is currently available , could help doctors decide whether the patients should undergo chemotherapy to prevent the cancer from . returning There are caveats : The test is expensive , and researchers don't yet know whether patients determined to be at high risk will live longer if they undergo . chemotherapy Still , this may be one of the very first examples of where we understood enough about the molecular biology of a cancer to truly personalize the treatment of patients and actually
Researchers in the US have developed a gene test that seems to be able to predict which early stage (stage I) non-small cell lung cancer patients have the poorest prognosis.
Health News Statins May Stave Off Liver Cancer in People With Hepatitis B Print E-mail THURSDAY , Jan . 26 HealthDay News Popular cholesterol-lowering statins may also lower risk for liver cancer among people with hepatitis B , a new study shows . Hepatitis B , an inflammation of the liver due to the hepatitis B virus , is one of the main causes of liver cancer . This is not the first time that statins have shown promise in reducing risk for cancer . Other studies have hinted that these drugs may play a role in preventing certain types of cancer , including breast cancer . In the new study of more than 33,000 individuals with hepatitis B followed from 1997 to 2008, those who took a statin were less likely to develop liver cancer , when compared to participants who were not prescribed
Cancer Research UK's Drug Development Office has opened the first trial of a new type of drug to treat children aged from six months to 18 years with acute leukaemia, who are no longer responding to treatment.
Here’s some great news about heart attacks and strokes for a change. The British Heart Foundation has released new statistics in January 2012 that show a 50% reduction in the number of heart attacks suffered by people in the United Kingdom over the period from 2002 to 2012. Furthermore, of those who do suffer [...]
Preoperative magnetic resonance imaging of the prostate changed the surgical plan in more than one in four patients undergoing robotic-assisted laparoscopic prostatectomy, according to the results of a single-center study.
Cancer Research Technology, the commercial arm of Cancer Research UK, has today launched Acublate Limited, a spin-out company which will develop a next-generation High Intensity Focused Ultrasound (HIFU) surgery device to treat a range of solid tumour types.
Ovarian cancer patients who carry BRCA1 or BRCA2 mutations are significantly more likely to survive the disease than women without these faulty genes, according to research published in the Journal of the American Medical Association.
Dutasteride, a drug already used to treat men with enlarged prostates, can also slow the growth of early-stage prostate cancer that hasn't spread, according to research from Canada.
Men with early prostate cancer had significantly less disease progression when treated with dutasteride (Avodart) as part of active surveillance, results of a randomized trial showed.
Maybe we are about to have another new treatment for advanced prostate cancer that will earn the coveted descriptor, “ON THE HORIZON.” OncoGenex Pharmaceuticals Inc. (OGXI) has said that they will be presenting preliminary data from their phase 2 trials evaluating their investigational compound OGX-427, in prostate and bladder cancer. The data will be presented [...]
Cancer Research UK scientists have created the first 3D structure of a key protein that protects against the development of cancer, according to research published in Nature Structural & Molecular Biology today.
Scientists have discovered the gene behind a rare skin condition that predisposes to oesophageal cancer, according to a study part-funded by Cancer Research UK.
As the post-Christmas January blues take hold, young people are risking damage to their health and appearance by using sunbeds on the recommendation of friends and family, according to a new survey by Cancer Research UK.
The use of the PSA as a prostate cancer screening tool has been a controversial issue for many years. Within the last year the issue has again come to the forefront of the public awareness, especially because of the recent move of the U.S Preventative Task Force to discourage using the PSA as a screening [...]
An international study has uncovered how secondary skin cancers sometimes develop in malignant melanoma patients who are treated with an experimental drug.
The authors of a study showing that hormone replacement therapy (HRT) increases the risk of breast cancer have defended their findings, following criticism from a team of experts linked to pharmaceutical companies that make the treatment.
Bavarian Nordic A/S (BAVA) announced on November 15, that its subsidiary, BN ImmunoTherapeutics has started the pivotal Phase 3 trial of PROSTVAC® for men with asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer. The trial is being conducted under a Special Protocol Assessment agreement with the FDA. Notice this trial has the same criteria as [...]
A fluorescent dye that can be sprayed onto the oesophagus - the food pipe - could be used to detect oesophageal cancer earlier and spare patients unnecessary treatment, according to research published today in Nature Medicine.
According to a an article published in the January 2012 issue of Cancer Prevention Research, estrogen may play a role in Melanoma recurrences! The article described a large cohort study of women who were put on an anti-estrogen therapy. The study concluded that those women on the anti-estrogen therapy had a lower risk of melanoma. [...]
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Neulasta (Pegfilgrastim) is used to reduce the chance of infection in people who have certain cancers and are also receiving chemotherapy medications, including taxotere for men being treated for advanced prostate cancer. Chemotherapy is designed to kill fast growing cells. However, it can’t tell the difference between cancer cells and fast-growing healthy cells, including red [...]
Researchers in the US have found that faults in a gene called HOXB13 seem to be more common in men with an inherited form of prostate cancer, and among those who develop the disease at a younger age.
We are about to finally get a more formal presentation of the great news we have all been waiting to hear. Medivation Inc. and Astellas Pharma Inc. announced that data from their Phase 3 AFFIRM trial, evaluating MDV3100 in men with advanced prostate cancer, will be highlighted in a late-breaking oral presentation at the upcoming [...]
Research into the most common type of brain tumour has uncovered a way to monitor the disease using the latest imaging technologies - dispensing with the need for invasive surgery.
Researchers at a children's hospital in Washington have identified the genetic mechanism behind the rapid development of retinoblastoma, a rare type of childhood eye cancer.
Cancer Research UK's Drug Development Office has re-launched a trial of a promising drug to treat inherited breast and ovarian cancer - but this time taken as a tablet by outpatients.
Considering yesterday’s post about the problems with fentanyl patches today’s post becomes even more scarey. The Food and Drug Administration (FDA) has made warns of opioid drug mix-up! According to the FDA pills, tablets, or caplets of Percocet and eight other opioid products packaged by Novartis for Endo Pharmaceuticals may have been mixed up, with [...]
Leslie from the Malecare Advanced Prostate Cancer On-line Support Group made a post today warning us that there have been significant malfunctions in fentanyl patches. Fentanyl patches are used to control severe pain, especially in men with very progressed advanced prostate cancer. According to the information posted some of these patches are malfunctioning causing accidental [...]
Today, 10 January 2012, Tesco is aiming to raise over £10 million to help Cancer Research UK's work to beat cancer by making Cancer Research UK its Charity of the Year in 2012.
In response to ALLMedPage Today's end-of-the-year survey, readers chose as top stories the changes in prostate and mammography screening, generic Lipitor, and the new class of oral anticoagulants, but the Affordable Care Act drew the most vocal comments.
Prostate cancer screening with prostate-specific antigen afforded no obvious prostate cancer mortality benefit during 13 years of follow-up in a large randomized trial.
Researchers at Ohio State University report that they have developed a new mathematical model for men with advanced prostate cancer who are on androgen deprivation therapy (ADT). This model could guide future treatment decisions for men with advanced prostate cancer, specifically, helping to decide which men would benefit from ADT on an intermittent schedule (IADT). [...]
A study funded by Cancer Research UK has provided a surprising insight into the development of a form of skin cancer called squamous cell carcinoma, or SCC.
Declining cancer incidence has translated into one million fewer cancer deaths over the past 20 years, according to data from the American Cancer Society.
Laboratory studies in the US have confirmed the promise of an experimental drug against a particularly aggressive form of neuroblastoma, the most common non-blood cancer in children.
Scientists based at Cancer Research UK's Cambridge Research Institute have discovered how receptors for the female sex hormone oestrogen attach to a different part of the DNA in breast cancer patients who are more likely to relapse, according to a study published in Nature today (Wednesday).
The Government will no longer face a legal challenge from four tobacco firms over its plans to ban tobacco displays from English shops, ministers have revealed.